Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY14 | Q15391 | 3/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1938664 | 0.87 | KDM4E (0.46) | P2RY14MAPT | |
| SCHEMBL1379237 | 0.86 | TP53 (0.48) | CYP1A2MAPTCYP3A4 | |
| SCHEMBL1938037 | 0.81 | KDM4E (0.47) | MAPT | |
| SCHEMBL1380793 | 0.79 | TP53 (0.49) | CYP1A2MAPTCYP3A4 | |
| SCHEMBL1380841 | 0.78 | KDM4E (0.46) | MAPT | |
| SCHEMBL1380634 | 0.77 | TP53 (0.48) | CYP1A2MAPTCYP3A4 | |
| SCHEMBL1939381 | 0.77 | P2RY14 (0.39) | P2RY14CYP1A2MAPTCYP3A4 | |
| SCHEMBL1939190 | 0.77 | P2RY14 (0.39) | P2RY14CYP1A2MAPTCYP3A4 | |
| SCHEMBL1381243 | 0.75 | KDM4E (0.49) | MAPT | |
| SCHEMBL1940646 | 0.75 | THRB (0.47) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4708438-B2 | — | — | 2011-06-22 | — | — | JP | claimed |