Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 10/20 | 0.44 |
| ▸ | DRD4 | P21917 | 10/20 | 0.44 |
| ▸ | DRD3 | P35462 | 10/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 3/20 | 0.41 |
| ▸ | DRD5 | P21918 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2337608 | 0.96 | GSK3B (0.49) | GSK3BCDK1CDK2KDM4EHSD17B10 | |
| SCHEMBL4497527 | 0.79 | KDM4E (0.50) | GSK3BCDK1CDK2KDM4EHSD17B10 | |
| SCHEMBL1461200 | 0.79 | GSK3B (0.61) | GSK3BCDK1CDK2KDM4EHSD17B10 | |
| SCHEMBL1379081 | 0.74 | DRD2 (0.35) | GSK3BCDK1CDK2KDM4EHSD17B10 | |
| SCHEMBL4392816 | 0.73 | GSK3B (0.61) | GSK3BCDK1CDK2KMT2AFGFR1 | |
| SCHEMBL4381668 | 0.73 | GSK3B (0.60) | GSK3BCDK1CDK2DRD1 | |
| SCHEMBL4500932 | 0.72 | GSK3B (0.62) | GSK3BCDK1CDK2KDM4EHSD17B10 | |
| SCHEMBL4392791 | 0.72 | GSK3B (0.76) | GSK3BCDK1CDK2KMT2A | |
| SCHEMBL2333341 | 0.72 | GSK3B (0.53) | GSK3BCDK1CDK2 | |
| SCHEMBL1461697 | 0.71 | GSK3B (0.82) | GSK3BCDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4764168-B2 | — | — | 2011-08-31 | — | — | JP | claimed |
| EP-1572200-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004062662-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-07-29 | — | — | WO | claimed |