Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.53 |
| ▸ | CDK1 | P06493 | 2/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338648 | 0.92 | GSK3B (0.58) | GSK3BCDK1CDK2PIK3CDPIK3R1 | |
| SCHEMBL2335996 | 0.92 | GSK3B (0.60) | GSK3BCDK1CDK2CDC7CYP1A2 | |
| SCHEMBL2337764 | 0.86 | GSK3B (0.60) | GSK3BCDK1CDK2LMNATP53 | |
| SCHEMBL6528308 | 0.84 | GSK3B (0.50) | GSK3BCDK1CDK2PIK3CDPIK3R1 | |
| SCHEMBL2337774 | 0.83 | GSK3B (0.57) | GSK3BCDK1CDK2CDC7FGFR1 | |
| SCHEMBL2338246 | 0.83 | GSK3B (0.59) | GSK3BCDK1CDK2CDC7FGFR1 | |
| SCHEMBL2333642 | 0.83 | GSK3B (0.67) | GSK3BCDK1CDK2CDC7CYP1A2 | |
| SCHEMBL1375621 | 0.82 | GSK3B (0.64) | GSK3BCDK1CDK2CDC7LMNA | |
| SCHEMBL1378947 | 0.81 | GSK3B (0.70) | GSK3BCDK1CDK2CDC7CYP1A2 | |
| SCHEMBL1375627 | 0.81 | GSK3B (0.58) | GSK3BCDK1CDK2CDC7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4764168-B2 | — | — | 2011-08-31 | — | — | JP | claimed |
| EP-1572200-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004062662-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-07-29 | — | — | WO | claimed |