Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.37 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338648 | 0.92 | GSK3B (0.58) | GSK3BCDK1CDK2CDC7PIK3CD | |
| SCHEMBL1377267 | 0.91 | GSK3B (0.59) | GSK3BCDK1CDK2CDC7ACHE | |
| SCHEMBL1376111 | 0.90 | GSK3B (0.49) | GSK3BCDK1CDK2CDC7ACHE | |
| SCHEMBL1376173 | 0.86 | GSK3B (0.57) | GSK3BCDK1CDK2CDC7ACHE | |
| SCHEMBL2334940 | 0.86 | GSK3B (0.56) | GSK3BCDK1CDK2CDC7ACHE | |
| SCHEMBL2337764 | 0.85 | GSK3B (0.60) | GSK3BCDK1CDK2 | |
| SCHEMBL1379088 | 0.84 | GSK3B (0.53) | GSK3BCDK1CDK2CDC7PIK3CD | |
| SCHEMBL6531233 | 0.84 | GSK3B (0.57) | GSK3BCDK1CDK2CDC7ACHE | |
| SCHEMBL1375621 | 0.81 | GSK3B (0.64) | GSK3BCDK1CDK2CDC7 | |
| SCHEMBL2333642 | 0.80 | GSK3B (0.67) | GSK3BCDK1CDK2CDC7CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572200-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004062662-A1 | AMINOINDAZOLE DERIVATIVES AND USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2004-07-29 | — | — | WO | disclosed |