Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.38 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.38 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.38 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13790815 | 0.92 | CYP1A1 (0.40) | EIF4A1CYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL13791080 | 0.90 | EIF4A1 (0.39) | ADORA3EIF4A1CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL3906470 | 0.89 | FFAR1 (0.39) | EIF4A1CYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL3914340 | 0.88 | EIF4A1 (0.39) | ADORA3EIF4A1CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL3909054 | 0.85 | EIF4A1 (0.40) | ADORA3EIF4A1CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL3111585 | 0.83 | CYP1A1 (0.43) | CYP1A1CYP1A2CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL3905655 | 0.82 | FFAR1 (0.54) | EIF4A1CYP1A2CYP2C19FFAR1ERAP1 | |
| SCHEMBL3915373 | 0.82 | FFAR1 (0.56) | CYP1A2CYP2C19FFAR1ERAP1SMN1; SMN2 | |
| SCHEMBL13791180 | 0.81 | CYP1A1 (0.38) | ADORA3EIF4A1CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL3904599 | 0.80 | FFAR1 (0.41) | EIF4A1CYP4F2CYP4A11FFAR1ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553867-B2 | Furan or thiophene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |