EIF4A1
Eukaryotic initiation factor 4A-I · P60842 · EIF4A1 on Sugi Atlas →
6,358 patent compounds predicted against EIF4A1, 3,577 high-confidence (nearest known ligand ≥ 0.5)
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours | |
|---|---|---|---|
| Silvestrol (SCHEMBL732092) | 1.00 | 19/20 | |
| Silvestrol (SCHEMBL5807124) | 1.00 | 19/20 | |
| SCHEMBL12455875 | 0.76 | 19/20 | |
| SCHEMBL12455880 | 0.76 | 19/20 | |
| SCHEMBL10305259 | 0.69 | 19/20 | |
| SCHEMBL12208427 | 0.69 | 19/20 | |
| SCHEMBL12190799 | 0.68 | 19/20 | |
| SCHEMBL5803471 | 0.68 | 19/20 | |
| SCHEMBL2616374 | 0.60 | 19/20 | |
| Aglafolin (SCHEMBL748617) | 1.00 | 18/20 | |
| Rocaglamide (SCHEMBL751061) | 1.00 | 18/20 | |
| Aglafolin (SCHEMBL752127) | 1.00 | 18/20 | |
| Rocaglamide (SCHEMBL752144) | 1.00 | 18/20 | |
| Rocaglamide (SCHEMBL10054686) | 1.00 | 18/20 | |
| SCHEMBL2629398 | 0.88 | 18/20 | |
| SCHEMBL12182311 | 0.87 | 18/20 | |
| SCHEMBL2629307 | 0.83 | 18/20 | |
| SCHEMBL2629286 | 0.74 | 18/20 | |
| Pannellin (SCHEMBL2463033) | 0.69 | 18/20 | |
| SCHEMBL12182058 | 0.68 | 18/20 |
Clinical trials — most relevant to EIF4A1 by text similarity (a relevance ranking, not an exhaustive list)
Related proteins — ESM-2 sequence neighbours (a EIF4A1 binder may also engage these)
| Protein | Name | Similarity | |
|---|---|---|---|
| P60843 | — | 1.000 | P60843 → |
| Q3SZ54 | — | 1.000 | Q3SZ54 → |
| Q4R8K5 | — | 1.000 | Q4R8K5 → |
| A5A6N4 | — | 1.000 | A5A6N4 → |
| Q5R4X1 | — | 1.000 | Q5R4X1 → |
| Q5R5F5 | — | 1.000 | Q5R5F5 → |
| A6M931 | — | 1.000 | A6M931 → |
| P10630 | — | 1.000 | P10630 → |
| Q3SZ65 | — | 1.000 | Q3SZ65 → |
| EIF4A2 | Eukaryotic initiation factor 4A-II | 1.000 | landscape → |
| Q5RKI1 | — | 1.000 | Q5RKI1 → |
| Q5ZM36 | — | 1.000 | Q5ZM36 → |
| Q4R4Y9 | — | 1.000 | Q4R4Y9 → |
| EIF4A3 | Eukaryotic initiation factor 4A-III | 1.000 | landscape → |
| Q9VHS8 | — | 1.000 | Q9VHS8 → |
| P29562 | — | 1.000 | P29562 → |
| Q3B8Q2 | — | 1.000 | Q3B8Q2 → |
| Q2NL22 | — | 1.000 | Q2NL22 → |
| Q5VNM3 | — | 1.000 | Q5VNM3 → |
| P0CQ70 | — | 1.000 | P0CQ70 → |
| B5DG42 | — | 1.000 | B5DG42 → |
| Q4R3Q1 | — | 1.000 | Q4R3Q1 → |
| Q4P184 | — | 1.000 | Q4P184 → |
| Q91VC3 | — | 1.000 | Q91VC3 → |
| Q8JFP1 | — | 1.000 | Q8JFP1 → |
| Q5B948 | — | 1.000 | Q5B948 → |
| B7ZTW1 | — | 1.000 | B7ZTW1 → |
| Q02748 | — | 1.000 | Q02748 → |
| A7EM88 | — | 0.999 | A7EM88 → |
| A1D7N3 | — | 0.999 | A1D7N3 → |