Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7240431 | 0.98 | KDM2B (0.43) | L3MBTL1KMT2AALDH1A1KDM2BGFER | |
| SCHEMBL16417106 | 0.86 | ALDH1A1 (0.47) | KMT2AALDH1A1PARP1MAPTMAOB | |
| SCHEMBL29429854 | 0.77 | KDM1A (0.41) | KMT2AALDH1A1HRH3MAPTMEN1 | |
| SCHEMBL31701380 | 0.76 | CA12 (0.47) | L3MBTL1KMT2AALDH1A1PARP1MAPT | |
| SCHEMBL20515231 | 0.75 | AKR1B1 (0.39) | L3MBTL1KMT2AALDH1A1PARP1MAPT | |
| SCHEMBL30098901 | 0.75 | AKR1B1 (0.39) | L3MBTL1ALDH1A1PARP1MAPT | |
| SCHEMBL3819996 | 0.74 | AKR1B1 (0.43) | L3MBTL1KMT2AALDH1A1PARP1MAPT | |
| SCHEMBL4564716 | 0.71 | KDM5A (0.41) | ALDH1A1CYP1A2 | |
| SCHEMBL2761915 | 0.71 | HRH3 (0.61) | L3MBTL1HRH3CYP1A2MAOB | |
| SCHEMBL2762023 | 0.71 | HRH3 (0.61) | L3MBTL1HRH3CYP1A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4703649-B2 | — | — | 2011-06-15 | — | — | JP | claimed |
| US-20080234270-A1 | Pyrrole Derivatives As Pharmaceutical Agents | EXELIXIS, INC. (US) | 2008-09-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234270-A1 | Pyrrole Derivatives As Pharmaceutical Agents | PRLHR, PTGDR, TACR1 | L3MBTL1 4875/4885KMT2A 4657/4885ALDH1A1 2251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.