Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403275 | 0.83 | MAPT (0.79) | MAPTKDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL30253505 | 0.80 | KDM4E (0.64) | MAPTKDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL431290 | 0.80 | KDM4E (0.64) | MAPTKDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL24415719 | 0.77 | KDM4E (0.61) | MAPTKDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL9859312 | 0.77 | CYSLTR1 (0.60) | MAPTKDM4ESMN1; SMN2KMT2ACNR2 | |
| SCHEMBL3954441 | 0.77 | MGAM (0.66) | MAPTKDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL6955948 | 0.75 | MGAM (0.63) | MAPTKDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5176927 | 0.75 | MGAM (0.63) | MAPTKDM4ESMN1; SMN2ALDH1A1GAA | |
| SCHEMBL14062630 | 0.74 | TDP1 (0.61) | MAPTALDH1A1TSHRKMT2AL3MBTL1 | |
| SCHEMBL4302912 | 0.74 | MGAM (0.61) | MAPTKDM4ESMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541467-B2 | N,N,N',N'-tetrakis(2-quinolylmethyl)ethylenediamine; reacting with Zinc ions; inhibition of photoinduced electron transfer (PET) | Yano, Shigenobu (JP) | 2009-06-02 | — | — | US | disclosed |