Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | CNR2 | P34972 | 4/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954441 | 0.86 | MGAM (0.66) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 | |
| SCHEMBL5176927 | 0.85 | MGAM (0.63) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 | |
| SCHEMBL27643442 | 0.83 | MAPT (0.61) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 | |
| SCHEMBL4302912 | 0.83 | MGAM (0.61) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 | |
| SCHEMBL30208641 | 0.83 | MGAM (0.61) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 | |
| SCHEMBL28908992 | 0.83 | MAPT (0.61) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 | |
| SCHEMBL4606005 | 0.83 | MGAM (0.61) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 | |
| SCHEMBL725183 | 0.83 | MGAM (0.61) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 | |
| SCHEMBL28990407 | 0.83 | MGAM (0.61) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 | |
| Hydrochloric Acid SCHEMBL16793838 | 0.81 | MGAM (0.59) | MGAMKDM4ESMN1; SMN2CNR2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765160-B1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | UNIV RAMOT (IL) | 2003-04-16 | — | — | EP | claimed |
| US-6096740-A | BLOCK N-METHYL-ASPARTATE | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 2000-08-01 | — | — | US | claimed |
| EP-0765160-A4 | — | — | 1997-04-09 | — | — | EP | claimed |
| EP-0765160-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY, AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. (IL) | 1997-04-02 | — | — | EP | claimed |
| WO-1995020958-A1 | DEXANABINOL DERIVATIVES AND THEIR USE AS NEUROPROTECTIVE PHARMACEUTICAL COMPOSITIONS | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 1995-08-10 | — | — | WO | claimed |