Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 6/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.34 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.34 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CD40 | P25942 | 1/20 | 0.34 |
| ▸ | CD40LG | P29965 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159105 | 0.89 | PHLPP2 (0.53) | PHLPP2THRBENPP2ALDH1A1HIF1A | |
| SCHEMBL13793163 | 0.89 | THRB (0.43) | PHLPP2THRBENPP2ALDH1A1HIF1A | |
| SCHEMBL14159117 | 0.88 | PHLPP2 (0.52) | PHLPP2THRBENPP2ALDH1A1HIF1A | |
| SCHEMBL13793184 | 0.87 | PHLPP2 (0.67) | PHLPP2THRBENPP2ALDH1A1HIF1A | |
| SCHEMBL13387188 | 0.83 | PHLPP2 (0.40) | PHLPP2THRBENPP2CD40CD40LG | |
| SCHEMBL24019203 | 0.82 | THRB (0.45) | PHLPP2THRBENPP2ALDH1A1HIF1A | |
| SCHEMBL13387236 | 0.80 | PHLPP2 (0.42) | PHLPP2THRBENPP2ALDH1A1HIF1A | |
| SCHEMBL14159116 | 0.80 | PHLPP2 (0.43) | PHLPP2THRBENPP2ALDH1A1HIF1A | |
| SCHEMBL13868300 | 0.79 | PHLPP2 (0.37) | PHLPP2THRBENPP2 | |
| SCHEMBL14546968 | 0.79 | PHLPP2 (0.48) | PHLPP2THRBENPP2ALDH1A1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7540883-B2 | good build-up, wash-off and light fastness and can be applied with dyestuffs in other colors; suitable for dyeing leather, wool, silk, nylon, cellulose fibers and cellulose fiber blends or interwoven fabrics | EVERLIGHT USA, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-20080282484-A1 | Reactive yellow dye composition | EVERLIGHT USA, INC. (US) | 2008-11-20 | — | — | US | disclosed |