Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 14/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796247 | 0.91 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13792943 | 0.85 | MCHR1 (0.55) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13795042 | 0.85 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13794525 | 0.84 | MCHR1 (0.58) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13794668 | 0.82 | NPY5R (0.49) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13796060 | 0.81 | MCHR1 (0.54) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13795996 | 0.81 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13795347 | 0.81 | MCHR1 (0.56) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13794836 | 0.80 | MCHR1 (0.56) | MCHR1ADRA2ANPY5RHTR1AADRA1A | |
| SCHEMBL13796685 | 0.79 | MCHR1 (0.59) | MCHR1ADRA2ANPY5RHTR1AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |