Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 8/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 12/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13795376 | 0.95 | MCHR1 (0.52) | NPY5RMCHR1ADRA2AMAPTKMT2A | |
| SCHEMBL13792943 | 0.92 | MCHR1 (0.55) | NPY5RMCHR1ADRA2AMEN1MAPT | |
| SCHEMBL13796247 | 0.89 | MCHR1 (0.48) | NPY5RMCHR1ADRA2APTGDR2KDM4E | |
| SCHEMBL13794836 | 0.87 | MCHR1 (0.56) | NPY5RMCHR1ADRA2AMEN1MAPT | |
| SCHEMBL13793237 | 0.86 | NPY5R (0.58) | NPY5RMCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL13795042 | 0.84 | MCHR1 (0.51) | NPY5RMCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL13794414 | 0.83 | MCHR1 (0.55) | NPY5RMCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL13794472 | 0.83 | MCHR1 (0.51) | NPY5RMCHR1ADRA2AHTR1AADRA1A | |
| SCHEMBL13797202 | 0.83 | NPY5R (0.53) | NPY5RMCHR1ADRA2ASMN1; SMN2HTR1A | |
| SCHEMBL13794574 | 0.82 | MCHR1 (0.49) | NPY5RMCHR1ADRA2APTGDR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |