Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | STING1 | Q86WV6 | 5/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.45 |
| ▸ | TK1 | P04183 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL852431 | 0.89 | PNP (0.50) | PNPADORA3POLBSTING1PDE3B | |
| SCHEMBL22278899 | 0.87 | ADORA3 (0.52) | PNPADORA3POLBSTING1PDE3B | |
| Entecavir Anhydrous SCHEMBL3436985 | 0.87 | ADORA3 (0.52) | PNPADORA3POLBSTING1PDE3B | |
| Entecavir Anhydrous SCHEMBL19644968 | 0.87 | ADORA3 (0.52) | PNPADORA3POLBSTING1PDE3B | |
| SCHEMBL9223882 | 0.87 | ADORA3 (0.52) | PNPADORA3POLBSTING1PDE3B | |
| Entecavir Anhydrous SCHEMBL24726395 | 0.87 | ADORA3 (0.52) | PNPADORA3POLBSTING1PDE3B | |
| Entecavir Anhydrous SCHEMBL21347868 | 0.87 | ADORA3 (0.52) | PNPADORA3POLBSTING1PDE3B | |
| Entecavir Anhydrous SCHEMBL21510623 | 0.87 | ADORA3 (0.52) | PNPADORA3POLBSTING1PDE3B | |
| Entecavir Anhydrous SCHEMBL17109567 | 0.87 | ADORA3 (0.52) | PNPADORA3POLBSTING1PDE3B | |
| Entecavir Anhydrous SCHEMBL17403367 | 0.87 | ADORA3 (0.52) | PNPADORA3POLBSTING1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7550619-B2 | Intermediates in the preparation of the antiviral agent [1S-(1α, 3α, 4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxmethyl)-2-methylenecyclopentyl]-6H-purin-6-one | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550619-B2 | Intermediates in the preparation of the antiviral agent [1S-(1α, 3α, 4β)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxmethyl)-2-methylenecyclopentyl]-6H-purin-6-one | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-06-23 | — | — | US | disclosed |