Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 9/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 8/20 | 0.55 |
| ▸ | BCHE | P06276 | 7/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13795757 | 0.92 | MCHR1 (0.57) | MCHR1ADRA2ABCHEACHEBACE1 | |
| SCHEMBL13796323 | 0.91 | MCHR1 (0.57) | MCHR1ADRA2ABCHEACHEBACE1 | |
| SCHEMBL13794879 | 0.91 | MCHR1 (0.60) | MCHR1ADRA2ABCHEACHEBACE1 | |
| SCHEMBL13795040 | 0.90 | ADRA2A (0.57) | MCHR1ADRA2ABCHENPY5RKDM4E | |
| SCHEMBL13794734 | 0.89 | MCHR1 (0.62) | MCHR1ADRA2ABCHEACHENPY5R | |
| SCHEMBL13794853 | 0.87 | MCHR1 (0.58) | MCHR1ADRA2ABCHEACHENPY5R | |
| SCHEMBL13792916 | 0.86 | MCHR1 (0.62) | MCHR1ADRA2ABCHEACHENPY5R | |
| SCHEMBL13796225 | 0.86 | MCHR1 (0.61) | MCHR1ADRA2ABCHEACHENPY5R | |
| SCHEMBL13797453 | 0.85 | MCHR1 (0.59) | MCHR1ADRA2ABCHEACHENPY5R | |
| SCHEMBL13794692 | 0.84 | APP (0.59) | MCHR1ADRA2ABCHEACHENPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |