Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 10/20 | 0.47 |
| ▸ | APP | P05067 | 9/20 | 0.47 |
| ▸ | BCHE | P06276 | 8/20 | 0.47 |
| ▸ | AQP1 | P29972 | 2/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14606892 | 1.00 | MRGPRX1 (0.51) | MRGPRX1NPY5RSLC6A4ACHEAPP | |
| SCHEMBL13796330 | 0.93 | MRGPRX1 (0.58) | MRGPRX1NPY5RSLC6A4ACHEAPP | |
| SCHEMBL13795833 | 0.92 | NPY5R (0.52) | MRGPRX1NPY5RSLC6A4ACHEAPP | |
| SCHEMBL13795622 | 0.90 | NPY5R (0.64) | MRGPRX1NPY5RSLC6A4ACHEAPP | |
| SCHEMBL13795878 | 0.90 | MRGPRX1 (0.53) | MRGPRX1NPY5RSLC6A4ACHEAPP | |
| SCHEMBL14606846 | 0.90 | MRGPRX1 (0.53) | MRGPRX1NPY5RSLC6A4ACHEAPP | |
| SCHEMBL13796342 | 0.89 | NPY5R (0.57) | MRGPRX1NPY5RSLC6A4ACHEAPP | |
| SCHEMBL13795588 | 0.89 | NPY5R (0.48) | MRGPRX1NPY5RSLC6A4ACHEAPP | |
| SCHEMBL13796090 | 0.88 | NPY5R (0.51) | MRGPRX1NPY5RSLC6A4ACHEAPP | |
| SCHEMBL13796077 | 0.88 | NPY5R (0.50) | MRGPRX1NPY5RSLC6A4ACHEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |