Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 5/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 10/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | ACACA | Q13085 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.44 |
| ▸ | AQP1 | P29972 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPY4R | P50391 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13796640 | 0.95 | ACACB (0.53) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796653 | 0.95 | ACACB (0.55) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13795909 | 0.93 | NPY5R (0.54) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796373 | 0.93 | ACACB (0.51) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796966 | 0.93 | ACACB (0.51) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796962 | 0.91 | ACACB (0.51) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796663 | 0.90 | ACACB (0.64) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL14606850 | 0.90 | ACACB (0.56) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796941 | 0.90 | ACACB (0.56) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796998 | 0.89 | ACACB (0.53) | ACACBNPY5RSLC6A4ACACAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |