Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.64 |
| ▸ | NPY5R | Q15761 | 12/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | ACACA | Q13085 | 3/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.45 |
| ▸ | NPY1R | P25929 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | AQP1 | P29972 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14606732 | 0.95 | ACACB (0.66) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13795896 | 0.95 | ACACB (0.66) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796653 | 0.92 | ACACB (0.55) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13795909 | 0.91 | NPY5R (0.54) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796962 | 0.91 | ACACB (0.51) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796963 | 0.91 | ACACB (0.52) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796966 | 0.90 | ACACB (0.51) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13795906 | 0.90 | ACACB (0.51) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796373 | 0.90 | ACACB (0.51) | ACACBNPY5RSLC6A4ACACAADRA2A | |
| SCHEMBL13796372 | 0.90 | ACACB (0.53) | ACACBNPY5RSLC6A4ACACAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |