SCHEMBL137961

SCHEMBL137961

Cl[Zr](Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.38
HTR6 P50406 1/20 0.37
SIGMAR1 Q99720 2/20 0.31
KDM4E B2RXH2 2/20 0.31
BRD4 O60885 1/20 0.31
CCL2 P13500 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31
CHRM2 P08172 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CHRM1 P11229 1/20 0.31
DRD2 P14416 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
NFKB1 P19838 1/20 0.31
CHRM3 P20309 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
ADRA1A P35348 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7941885 0.98 HTR2A (0.36) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL4445268 0.96 HTR2A (0.35) HTR2AHTR6SIGMAR1KDM4EBRD4
Ethylene SCHEMBL2231954 0.96 HTR2A (0.35) HTR2AHTR6
Propane SCHEMBL22261431 0.92 HTR2A (0.37) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL4453772 0.92 HTR2A (0.33) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL4453982 0.89 HTR6 (0.32) HTR2AHTR6SIGMAR1
SCHEMBL9064184 0.88 HTR2A (0.35) HTR2AHTR6
SCHEMBL550007 0.87 HTR2A (0.38) HTR2AHTR6SIGMAR1KDM4EBRD4
SCHEMBL21681768 0.87 HTR6 (0.33) HTR2AHTR6
SCHEMBL795334 0.85 HTR6 (0.32) HTR2AHTR6CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2776 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3697822-B1 MIXED CATALYSTS WITH UNBRIDGED HAFNOCENES WITH -CH2-SIME3 MOIETIES EXXONMOBIL CHEMICAL PATENTS INC (US) 2025-07-30 EP claimed
US-20230357454-A1 Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-09 US claimed
EP-4192888-A1 METHODS FOR DELIVERY OF NON-AROMATIC SOLUTIONS TO POLYMERIZATION REACTORS ExxonMobil Chemical Patents Inc. (US) 2023-06-14 EP claimed
US-11634513-B2 Process for preparing catalysts and catalyst compositions FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2023-04-25 US claimed
EP-3583140-B1 SUPPORTED CATALYST SYSTEMS AND PROCESSES FOR USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-03-08 EP claimed
US-20220242976-A1 PROCESS FOR PREPARING CATALYSTS AND CATALYST COMPOSITIONS FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2022-08-04 US claimed
WO-2022035484-A1 METHODS FOR DELIVERY OF NON-AROMATIC SOLUTIONS TO POLYMERIZATION REACTORS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-02-17 WO claimed
US-11193008-B2 Methods for making polyolefin polymer compositions EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-12-07 US claimed
US-11117991-B2 Methods for operating a polymerization reactor UNIVATION TECHNOLOGIES, LLC (US) 2021-09-14 US claimed
US-10822434-B2 Catalyst systems and polymerization processes for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-11-03 US claimed
EP-0389981-B1 Process for producing styrene-based polymer IDEMITSU KOSAN CO (JP) 1994-09-07 EP claimed
US-5332706-A Alumoxane in a silica support, activated metallocene, ethylene polymerization catalyst MOBIL OIL CORPORATION (US) 1994-07-26 US claimed
WO-1993024539-A1 REACTIVE, LOW MOLECULAR WEIGHT, VISCOUS POLY(1-OLEFINS) AND COPOLY(1-OLEFINS) AND THEIR METHOD OF MANUFACTURE AMOCO CORPORATION (US) 1993-12-09 WO claimed
US-5258475-A Catalyst systems for polymerization and copolymerization of olefins MOBIL OIL CORPORATION (US) 1993-11-02 US claimed
EP-0303519-B1 POLYMERIZATION OF ETHYLENE MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-03-31 EP claimed
EP-0474391-A2 Polyolefins NIPPON OIL CO. LTD. (JP) 1992-03-11 EP claimed
US-5023304-A Using coordination catalyst; highly syndiotactic IDEMITSU KOSAN CO., LTD. (JP) 1991-06-11 US claimed
EP-0389981-A2 Process for producing styrene-based polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-10-03 EP claimed
US-4931517-A Polymerization of ethylene MITSUBISHI PETROCHEMICAL COMPANY LIMITED (JP) 1990-06-05 US claimed
EP-0303519-A1 Polymerization of ethylene MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1989-02-15 EP claimed