Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.87 |
| ▸ | ADRA2A | P08913 | 19/20 | 0.87 |
| ▸ | NPY5R | Q15761 | 17/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941081 | 0.93 | ADRA2A (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3938377 | 0.93 | ADRA2A (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL3938380 | 0.93 | ADRA2A (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL13796396 | 0.93 | MCHR1 (0.85) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL3939654 | 0.92 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL3939657 | 0.92 | MCHR1 (1.00) | MCHR1ADRA2ANPY5R | |
| SCHEMBL13796899 | 0.91 | MCHR1 (0.71) | MCHR1ADRA2ANPY5R | |
| SCHEMBL13796398 | 0.88 | MCHR1 (0.77) | MCHR1ADRA2ANPY5R | |
| Hydrochloric Acid SCHEMBL6612074 | 0.86 | ADRA2A (0.88) | MCHR1ADRA2ANPY5R | |
| SCHEMBL13795799 | 0.86 | MCHR1 (0.80) | MCHR1ADRA2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |