SCHEMBL137969

SCHEMBL137969

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](OC(=O)O[C@H]5CC[C@@]6(C)C(=CC[C@H]7[C@@H]8CC[C@H]([C@H](C)CCCC(C)C)[C@@]8(C)CC[C@@H]76)C5)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.80

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLA1 P09884 1/20 0.79
CYP46A1 Q9Y6A2 2/20 0.78
OSBP P22059 3/20 0.73
USP2 O75604 2/20 0.73
RORC P51449 2/20 0.73
LMNA P02545 1/20 0.73
ABCB1 P08183 1/20 0.73
OSBP2 Q969R2 1/20 0.73
NR1H3 Q13133 4/20 0.64
CYP1A2 P05177 1/20 0.63
NPC1L1 Q9UHC9 2/20 0.63
NPC1 O15118 1/20 0.63
GRIN1 Q05586 1/20 0.62
GRIN2A Q12879 1/20 0.62
PLA2G2A P14555 1/20 0.62
GBA1 P04062 2/20 0.61
UGCG Q16739 2/20 0.61
GBA2 Q9HCG7 2/20 0.61
EPHA2 P29317 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6419070 1.00 POLA1 (0.79) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL29855293 0.98 POLA1 (0.77) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL3204391 0.98 POLA1 (0.77) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL13615226 0.98 POLA1 (0.77) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL249325 0.98 POLA1 (0.77) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL23069792 0.98 POLA1 (0.77) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL17817630 0.98 POLA1 (0.77) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL19608051 0.98 POLA1 (0.77) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL249326 0.98 POLA1 (0.77) POLA1CYP46A1OSBPUSP2RORC
SCHEMBL16330224 0.96 POLA1 (0.73) POLA1CYP46A1OSBPUSP2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 920 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119044072-A Liquid crystal sensor for detecting formaldehyde gas and preparation method thereof 江南大学 2024-11-29 CN claimed
US-20240189230-A1 PALM FOR THE TREATMENT OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY INCIDENTAL TO THE TREATMENT OF CANCER PEPTINOVO BIOPHARMA INC. 2024-06-13 US claimed
US-20240174878-A1 Thermochromic Liquid Crystal Inks SUN CHEMICAL B.V. (NL) 2024-05-30 US claimed
CN-117789993-A Establishment and application of gastric cancer prediction model based on tongue fur metabolite 浙江省肿瘤医院 2024-03-29 CN claimed
US-20230265123-A1 PEPTIDES AND FORMULATIONS FOR CANCER TREATMENT PEPTINOVO BIOPHARMA INC. 2023-08-24 US claimed
EP-4196166-A2 PEPTIDES AND FORMULATIONS FOR CANCER TREATMENT Peptinovo Biopharma Inc. (US) 2023-06-21 EP claimed
CN-114908575-B Liquid crystal ultraviolet-resistant finishing agent and application thereof to textiles 江南大学 2023-06-16 CN claimed
CN-116206540-A Multi-mode display layer made of up-conversion liquid crystal microcapsules and display application 苏州科技大学 2023-06-02 CN claimed
CN-113777061-B Acetone gas fiber sensor visible to naked eyes and preparation method thereof 江南大学 2023-01-31 CN claimed
CN-114908575-A Liquid crystal ultraviolet-resistant finishing agent and application thereof to textiles 江南大学 2022-08-16 CN claimed
WO-2021046004-A1 THERMOCHROMIC LIQUID CRYSTAL INKS AND COATINGS SUN CHEMICAL CORPORATION (US) 2021-03-11 WO claimed
CN-112175632-A Temperature-sensitive color developing liquid crystal microcapsule and preparation method thereof 江苏集萃智能液晶科技有限公司 2021-01-05 CN claimed
CN-111905663-A Temperature-sensitive color developing liquid crystal microcapsule and preparation method thereof 苏州和萃新材料有限公司 2020-11-10 CN claimed
CN-111568631-A Cooling paste with temperature indication function and preparation method thereof 武汉中科先进技术研究院有限公司 2020-08-25 CN claimed
CN-111560258-A Temperature-sensitive color developing liquid crystal microcapsule and preparation method thereof 江苏集萃智能液晶科技有限公司 2020-08-21 CN claimed
CN-109375306-B Method for manufacturing cholesteric liquid crystal polymer sheet 厦门大学 2020-04-10 CN claimed
CN-1648623-A Thermal sensitive composition and disposable thermometer made therefrom TENGTAI APPLIED SCIENCE AND TE (CN) 2005-08-03 CN claimed
US-4835899-A Fishing lure with temperature responsive color change HELTON DOYLE D (US) 1989-06-06 US claimed
US-4731948-A Fishing lure with temperature responsive color change HELTON DOYLE D (US) 1988-03-22 US claimed
US-3975287-A Liquid crystal composition for electric field indication KANSAI PAINT COMPANY, LTD. (JA) 1976-08-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240189230-A1 PALM FOR THE TREATMENT OF CHEMOTHERAPY-INDUCED PERIPHERAL NEUROPATHY INCIDENTAL TO THE TREATMENT OF CANCER SGMS1, PHOSPHO1, SGMS2 POLA1 2489/4885CYP46A1 3449/4885OSBP 3745/4885
US-20230265123-A1 PEPTIDES AND FORMULATIONS FOR CANCER TREATMENT PHOSPHO1, NGLY1, ANXA11 POLA1 2141/4885CYP46A1 1579/4885OSBP 301/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.