SCHEMBL13796937 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	NPY5R	Q15761	15/20	0.57

▸	ADRA2A	P08913	6/20	0.57

▸	MCHR1	Q99705	6/20	0.57

▸	AQP1	P29972	2/20	0.57

▸	ALDH1A1	P00352	1/20	0.57

▸	MAPT	P10636	1/20	0.57

▸	HPGD	P15428	1/20	0.57

▸	NPY1R	P25929	1/20	0.57

▸	NPY2R	P49146	1/20	0.57

▸	NPY4R	P50391	1/20	0.57

▸	TDP1	Q9NUW8	1/20	0.57

▸	SLC6A4	P31645	2/20	0.49

▸	SOS1	Q07889	2/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13795829	0.90	NPY5R (0.63)	NPY5RADRA2AMCHR1AQP1ALDH1A1
SCHEMBL13796914	0.90	NPY5R (0.58)	NPY5RADRA2AMCHR1AQP1ALDH1A1
SCHEMBL13796261	0.90	NPY5R (0.71)	NPY5RADRA2AMCHR1AQP1ALDH1A1
SCHEMBL13796880	0.90	NPY5R (0.60)	NPY5RADRA2AMCHR1AQP1ALDH1A1
SCHEMBL13796241	0.89	AQP1 (0.63)	NPY5RADRA2AMCHR1AQP1ALDH1A1
SCHEMBL13795804	0.88	NPY5R (0.54)	NPY5RADRA2AMCHR1AQP1ALDH1A1
SCHEMBL13796263	0.88	NPY5R (0.58)	NPY5RADRA2AMCHR1AQP1ALDH1A1
SCHEMBL13796283	0.88	NPY5R (0.60)	NPY5RADRA2AMCHR1AQP1ALDH1A1
SCHEMBL13795808	0.88	NPY5R (0.57)	NPY5RADRA2AMCHR1AQP1ALDH1A1
SCHEMBL14606901	0.87	NPY5R (0.55)	NPY5RADRA2AMCHR1AQP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-7544690-B2	MCH receptor antagonists	TAISHO PHARMACEUTICAL CO., LTD. (JP)	2009-06-09	—	—	US	disclosed
US-7544690-B2	MCH receptor antagonists	TAISHO PHARMACEUTICAL CO., LTD. (JP)	2009-06-09	—	—	US	disclosed