Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.49 |
| ▸ | ACP1 | P24666 | 6/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPRF | P10586 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2542491 | 0.84 | PIM1 (1.00) | PIM1PTPN1ACP1ENPP2PTPN2 | |
| SCHEMBL2542488 | 0.84 | PIM1 (1.00) | PIM1PTPN1ACP1ENPP2PTPN2 | |
| SCHEMBL2542486 | 0.84 | PIM1 (1.00) | PIM1PTPN1ACP1ENPP2PTPN2 | |
| SCHEMBL12259741 | 0.76 | PIM1 (0.79) | PIM1PTPN1ACP1ENPP2PTPN2 | |
| SCHEMBL5463878 | 0.72 | PIM1 (0.62) | PIM1PTPN1ACP1ENPP2PTPN2 | |
| SCHEMBL5463876 | 0.72 | PIM1 (0.62) | PIM1PTPN1ACP1ENPP2PTPN2 | |
| SCHEMBL15682754 | 0.72 | PIM1 (0.62) | PIM1PTPN1ACP1ENPP2PPARG | |
| SCHEMBL17059998 | 0.72 | PIM1 (0.62) | PIM1PTPN1ACP1ENPP2PPARG | |
| SCHEMBL12237152 | 0.72 | PIM1 (0.77) | PIM1PTPN1ACP1ENPP2PPARG | |
| SCHEMBL26709501 | 0.70 | PIM1 (0.60) | PIM1PTPN1ACP1ENPP2PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009064486-A9 | INHIBITORS OF PIM PROTEIN KINASES, COMPOSITIONS, AND METHODS FOR TREATING CANCER | MUSC FOUND FOR RES DEV (US) | 2009-07-16 | — | — | WO | disclosed |