Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.48 |
| ▸ | ACP1 | P24666 | 4/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411695 | 1.00 | PIM1 (0.60) | PIM1PPARGNLRP3MEN1ALDH1A1 | |
| SCHEMBL26709466 | 0.85 | NLRP3 (0.71) | PIM1PPARGNLRP3MEN1ALDH1A1 | |
| SCHEMBL28979066 | 0.85 | NLRP3 (0.71) | PIM1PPARGNLRP3MEN1ALDH1A1 | |
| SCHEMBL29411713 | 0.85 | PTPN1 (0.60) | PPARGNLRP3MEN1ALDH1A1POLB | |
| SCHEMBL28979085 | 0.85 | PTPN1 (0.60) | PPARGNLRP3MEN1ALDH1A1POLB | |
| SCHEMBL26709485 | 0.85 | PTPN1 (0.60) | PPARGNLRP3MEN1ALDH1A1POLB | |
| SCHEMBL26606767 | 0.84 | MEN1 (0.64) | PIM1PPARGMEN1POLBMAPK1 | |
| SCHEMBL17059998 | 0.83 | PIM1 (0.62) | PIM1PPARGNLRP3MEN1ALDH1A1 | |
| SCHEMBL15682754 | 0.83 | PIM1 (0.62) | PIM1PPARGNLRP3MEN1ALDH1A1 | |
| SCHEMBL29411674 | 0.82 | ENPP2 (0.53) | PIM1PPARGNLRP3MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230339871-A1 | COMPOUNDS AND METHODS OF MODULATING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | METREA BIOSCIENCES INC (US) | 2023-10-26 | — | — | US | claimed |
| US-20230339871-A1 | COMPOUNDS AND METHODS OF MODULATING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | METREA BIOSCIENCES INC (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230339871-A1 | COMPOUNDS AND METHODS OF MODULATING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | METREA BIOSCIENCES INC (US) | 2023-10-26 | — | — | US | disclosed |
| US-20230339871-A1 | COMPOUNDS AND METHODS OF MODULATING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | METREA BIOSCIENCES INC (US) | 2023-10-26 | — | — | US | disclosed |
| EP-4200286-A1 | COMPOUNDS AND METHODS OF MODULATING 17BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | Metrea Biosciences, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| CN-115916762-A | Compounds and methods for modulating 17 beta-hydroxysteroid dehydrogenase type 13 | 梅特雷亚生物科学股份有限公司 | 2023-04-04 | — | — | CN | disclosed |
| WO-2022040324-A1 | COMPOUNDS AND METHODS OF MODULATING 17β-ΗYDROXYSTEROID DEHYDROGENASE TYPE 13 | METREA BIOSCIENCES, INC. (US) | 2022-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230339871-A1 | COMPOUNDS AND METHODS OF MODULATING 17B-HYDROXYSTEROID DEHYDROGENASE TYPE 13 | HSD17B1, HSD17B13, HSD17B11 | PIM1 4359/4885PPARG 871/4885NLRP3 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.