Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 13/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 13/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 11/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13797300 | 0.90 | ADRA2A (0.57) | ADRA2AMCHR1NPY5R | |
| SCHEMBL13792913 | 0.88 | ADRA2A (0.59) | ADRA2AMCHR1NPY5R | |
| SCHEMBL13797263 | 0.87 | ADRA2A (0.55) | ADRA2AMCHR1NPY5R | |
| SCHEMBL14606998 | 0.85 | ADRA2A (0.53) | ADRA2AMCHR1NPY5R | |
| SCHEMBL13797260 | 0.83 | ADRA2A (0.57) | ADRA2AMCHR1NPY5R | |
| SCHEMBL13797231 | 0.83 | ADRA2A (0.52) | ADRA2AMCHR1NPY5R | |
| SCHEMBL13797262 | 0.83 | ADRA2A (0.56) | ADRA2AMCHR1NPY5R | |
| SCHEMBL13797267 | 0.80 | ADRA2A (0.54) | ADRA2AMCHR1NPY5R | |
| SCHEMBL13797269 | 0.80 | ADRA2A (0.55) | ADRA2AMCHR1NPY5R | |
| SCHEMBL13797266 | 0.80 | ADRA2A (0.62) | ADRA2AMCHR1NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544690-B2 | MCH receptor antagonists | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |