Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 10/20 | 0.73 |
| ▸ | AR | P10275 | 9/20 | 0.73 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942762 | 1.00 | PGR (0.73) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12942783 | 1.00 | PGR (0.73) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12942772 | 1.00 | PGR (0.73) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12942812 | 0.88 | PGR (0.56) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL16545328 | 0.85 | PGR (0.56) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12942737 | 0.85 | PGR (0.56) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12942848 | 0.85 | PGR (0.74) | PGRARNR3C2CYP19A1LMNA | |
| SCHEMBL12942787 | 0.85 | AR (0.74) | PGRARNR3C2LMNA | |
| SCHEMBL12942799 | 0.85 | AR (0.74) | PGRARNR3C2LMNA | |
| SCHEMBL12942816 | 0.85 | PGR (0.56) | PGRARNR3C2CYP19A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083271-A1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |