Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.73 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.31 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14601670 | 0.92 | CYP2C19 (0.86) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL20829072 | 0.91 | LMNA (0.76) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL10329899 | 0.91 | LMNA (0.88) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL20350848 | 0.90 | LMNA (0.86) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL20034186 | 0.90 | LMNA (0.82) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL21164396 | 0.87 | CYP2C19 (0.78) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL24169901 | 0.87 | LMNA (0.73) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL15293708 | 0.86 | CYP2C19 (0.88) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL15293707 | 0.86 | LMNA (0.88) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL19915482 | 0.85 | CYP2C19 (0.86) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009081169-A2 | BIODEGRADABLE CONTRAST AGENTS | IOPHARMA TECHNOLOGIES AB (SE) | 2009-07-02 | — | — | WO | disclosed |