Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.58 |
| ▸ | PGR | P06401 | 15/20 | 0.58 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942851 | 1.00 | AR (0.58) | ARPGRNR3C2LMNAABCC4 | |
| SCHEMBL12942763 | 0.89 | AR (0.58) | ARPGRNR3C2LMNAABCC4 | |
| SCHEMBL12942787 | 0.88 | AR (0.74) | ARPGRNR3C2LMNA | |
| SCHEMBL12942799 | 0.88 | AR (0.74) | ARPGRNR3C2LMNA | |
| SCHEMBL12942813 | 0.88 | AR (0.60) | ARPGRNR3C2LMNAABCC4 | |
| SCHEMBL12942854 | 0.86 | AR (0.44) | ARPGRNR3C2 | |
| SCHEMBL12942812 | 0.85 | PGR (0.56) | ARPGRNR3C2LMNAABCB11 | |
| SCHEMBL12998916 | 0.83 | AR (0.82) | ARPGRNR3C2LMNAABCC4 | |
| SCHEMBL12942815 | 0.83 | AR (0.46) | ARPGRNR3C2LMNAABCC4 | |
| SCHEMBL15417408 | 0.80 | AR (0.52) | ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083271-A1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |