Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 18/20 | 0.61 |
| ▸ | AR | P10275 | 17/20 | 0.61 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942801 | 1.00 | PGR (0.61) | PGRARNR3C2MEN1CYP3A4 | |
| SCHEMBL12942817 | 1.00 | PGR (0.61) | PGRARNR3C2MEN1CYP3A4 | |
| SCHEMBL12942858 | 1.00 | PGR (0.61) | PGRARNR3C2MEN1CYP3A4 | |
| SCHEMBL12942857 | 1.00 | PGR (0.61) | PGRARNR3C2MEN1CYP3A4 | |
| SCHEMBL12942800 | 0.90 | AR (0.58) | PGRARNR3C2 | |
| SCHEMBL12942740 | 0.90 | AR (0.58) | PGRARNR3C2 | |
| SCHEMBL12942709 | 0.90 | AR (0.58) | PGRARNR3C2 | |
| SCHEMBL12942710 | 0.89 | PGR (0.48) | PGRARNR3C2 | |
| SCHEMBL12942852 | 0.89 | PGR (0.58) | PGRARNR3C2MEN1CYP3A4 | |
| SCHEMBL12942782 | 0.89 | PGR (0.58) | PGRARNR3C2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083271-A1 | 15,16-METHYLENE-17-(1'-PROPENYL)-17,3'-OXIDOESTRA-4-EN-3-ONE DERIVATIVE, USE THEREOF, AND MEDICAMENT CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | disclosed |