Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5271653 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 | |
| SCHEMBL18378763 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 | |
| SCHEMBL10347198 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 | |
| SCHEMBL15796773 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 | |
| SCHEMBL5271657 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 | |
| SCHEMBL4679055 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 | |
| SCHEMBL4206354 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 | |
| SCHEMBL18378981 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 | |
| SCHEMBL3880771 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 | |
| SCHEMBL214490 | 1.00 | NAAA (0.55) | NAAAEPHX1TSHRHTR2CHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553825-B2 | Anti-proliferative compounds, compositions, and methods of use thereof | GILEAD SCIENCES, INC. (US) | 2009-06-30 | — | — | US | disclosed |