Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28273457 | 0.75 | CHRNA4 (0.44) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| SCHEMBL5792027 | 0.73 | GAA (0.36) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| SCHEMBL109365 | 0.73 | — | — | |
| SCHEMBL1323514 | 0.73 | — | — | |
| Acetone SCHEMBL2954541 | 0.72 | CHRNA4 (0.40) | CHRNA4RAPGEF3RAPGEF4RAB9APOLB | |
| Benzene SCHEMBL28148287 | 0.71 | KDM4E (0.46) | CHRNA4RAPGEF3RAPGEF4POLBL3MBTL1 | |
| SCHEMBL325207 | 0.71 | — | — | |
| SCHEMBL11166684 | 0.71 | — | — | |
| SCHEMBL826240 | 0.71 | — | — | |
| SCHEMBL2122427 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11351264-B2 | PAR2 mimetic peptides and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-06-07 | — | — | US | disclosed |
| US-20190117785-A1 | PAR2 MIMETIC PEPTIDES AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2019-04-25 | — | — | US | disclosed |
| US-8450301-B2 | Piperazine compounds with a herbicidal action | BASF SE (DE) | 2013-05-28 | — | — | US | disclosed |
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | BASF SE (DE) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156553-A1 | PIPERAZINE COMPOUNDS WITH A HERBICIDAL ACTION | DDT, CAT, CIP2A | CHRNA4 3488/4885RAPGEF3 841/4885RAPGEF4 1112/4885 |
| US-11351264-B2 | PAR2 mimetic peptides and uses thereof | F2RL1, F2R, F2RL3 | CHRNA4 3899/4885RAPGEF3 824/4885RAPGEF4 1199/4885 |
| US-20190117785-A1 | PAR2 MIMETIC PEPTIDES AND USES THEREOF | F2RL1, F2R, F2RL3 | CHRNA4 3899/4885RAPGEF3 824/4885RAPGEF4 1199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.