Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PI4KA | P42356 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.57 |
| ▸ | XDH | P47989 | 6/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3867527 | 0.87 | KDM4E (0.67) | RAB9AKDM4EHSD17B10NPC1HTT | |
| SCHEMBL3869670 | 0.86 | KDM4E (0.63) | RAB9AKDM4EHSD17B10NPC1HTT | |
| SCHEMBL3867283 | 0.86 | XDH (0.73) | RAB9AKDM4EHSD17B10NPC1HTT | |
| SCHEMBL13790294 | 0.82 | KDM4E (0.64) | RAB9AKDM4EHSD17B10NPC1HTT | |
| SCHEMBL13790429 | 0.81 | MEN1 (0.60) | RAB9AKDM4EHSD17B10NPC1HTT | |
| SCHEMBL13790354 | 0.81 | KDM4E (0.53) | RAB9AKDM4EHSD17B10NPC1HTT | |
| SCHEMBL13790269 | 0.80 | XDH (0.55) | RAB9AKDM4EHSD17B10NPC1HTT | |
| SCHEMBL13790384 | 0.80 | XDH (0.52) | RAB9AKDM4EHSD17B10NPC1HTT | |
| SCHEMBL13790393 | 0.78 | NPC1 (1.00) | RAB9AKDM4EHSD17B10NPC1HTT | |
| SCHEMBL3879802 | 0.78 | KDM4E (0.71) | RAB9AKDM4EHSD17B10NPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163520-A1 | MNK1 or MNK2 Inhibitors | DEVELOGEN AKTIENGESELLSCHAFT (DE) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163520-A1 | MNK1 or MNK2 Inhibitors | NEK9, CMPK1, NEK2 | RAB9A 2597/4885KDM4E 2821/4885HSD17B10 3021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.