Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 16/20 | 0.83 |
| ▸ | MMP2 | P08253 | 13/20 | 0.83 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8576707 | 1.00 | MMP9 (0.83) | MMP9MMP2KCNA5MEN1POLB | |
| SCHEMBL8603495 | 1.00 | MMP9 (0.83) | MMP9MMP2KCNA5MEN1POLB | |
| SCHEMBL6720186 | 0.92 | MMP9 (0.89) | MMP9MMP2KCNA5MEN1POLB | |
| SCHEMBL5191094 | 0.92 | MMP9 (0.89) | MMP9MMP2KCNA5MEN1POLB | |
| SCHEMBL7301154 | 0.91 | MMP9 (1.00) | MMP9MMP2KCNA5MEN1POLB | |
| SCHEMBL7468990 | 0.89 | MMP9 (0.83) | MMP9MMP2KCNA5MEN1POLB | |
| SCHEMBL7468980 | 0.89 | MMP9 (0.83) | MMP9MMP2KCNA5MEN1POLB | |
| SCHEMBL3154764 | 0.89 | MMP9 (0.88) | MMP9MMP2KCNA5MEN1POLB | |
| SCHEMBL22500283 | 0.89 | MMP9 (0.83) | MMP9MMP2KCNA5MEN1POLB | |
| SCHEMBL22500298 | 0.89 | MMP9 (0.83) | MMP9MMP2KCNA5MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090142845-A1 | FLOW REACTOR METHOD AND APPARATUS | SMITHKLINE BEECHAM CORPORATION | 2009-06-04 | — | — | US | disclosed |
| US-20090142845-A1 | FLOW REACTOR METHOD AND APPARATUS | SMITHKLINE BEECHAM CORPORATION | 2009-06-04 | — | — | US | disclosed |