⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3249847 | 0.60 | — | — | |
| SCHEMBL4927956 | 0.58 | — | — | |
| SCHEMBL9549440 | 0.47 | INMT (0.37) | — | |
| SCHEMBL7269741 | 0.47 | — | — | |
| SCHEMBL31175398 | 0.46 | — | — | |
| SCHEMBL18773169 | 0.46 | — | — | |
| SCHEMBL10017669 | 0.39 | — | — | |
| Benzene SCHEMBL29650150 | 0.39 | — | — | |
| Benzene SCHEMBL29757764 | 0.39 | TSHR (0.75) | — | |
| Benzene SCHEMBL5314229 | 0.35 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6156 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199679-A1 | ADENOSINE DERIVATIVE HAVING ANTAGONISTIC ACTION ON A2A AND A3 ADENOSINE RECEPTORS AND METHOD FOR PREPARING SAME | FUTURE MEDICINE CO., LTD. (KR) | 2024-06-20 | — | — | US | claimed |
| EP-4382101-A1 | N-ACYLHYDRAZONE COMPOUNDS CAPABLE OF INHIBITING NAV1.7 AND/OR NAV1.8, PROCESSES FOR THE PREPARATION THEREOF, COMPOSITIONS, USES, METHODS FOR TREATMENT USING SAME, AND KITS | Eurofarma Laboratórios S.A. (BR) | 2024-06-12 | — | — | EP | claimed |
| CN-118076347-A | N-acylhydrazone compounds capable of inhibiting NAV 1.7 and/or NAV 1.8, methods of making, compositions, uses, methods of treatment and kits using the same | 欧罗法玛实验室股份公司 | 2024-05-24 | — | — | CN | claimed |
| US-20240109916-A1 | CYTOTOXIC AGENTS | PHEON THERAPEUTICS LTD (GB) | 2024-04-04 | — | — | US | claimed |
| CN-117658982-A | Novel CDK12/13 covalent inhibitor or pharmaceutical composition and application thereof | 中国科学院上海有机化学研究所 | 2024-03-08 | — | — | CN | claimed |
| EP-4296273-A1 | ADENOSINE DERIVATIVE HAVING ANTAGONISTIC ACTION ON A2A AND A3 ADENOSINE RECEPTORS AND METHOD FOR PREPARING SAME | Future Medicine Co., Ltd. (KR) | 2023-12-27 | — | — | EP | claimed |
| CN-113861103-B | Method for synthesizing pyridine, bipyridine and terpyridine ligand | 南方科技大学 | 2023-12-22 | — | — | CN | claimed |
| US-11827632-B2 | NLRP3 modulators | INNATE TUMOR IMMUNITY, INC (US) | 2023-11-28 | — | — | US | claimed |
| CN-117083286-A | Pair A 2A A is a 3 Adenosine derivatives having antagonism to adenosine receptor and process for preparing same | 未来制药有限公司 | 2023-11-17 | — | — | CN | claimed |
| US-20230339866-A1 | Quinazoline compounds and the use thereof in the treatment of cancer | TroBio Therapeutics Pty Ltd (AU) | 2023-10-26 | — | — | US | claimed |
| US-4355823-A | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1982-10-26 | — | — | US | claimed |
| EP-0049999-A2 | Cyclic compounds and their preparation and use | BEECHAM GROUP PLC (GB) | 1982-04-21 | — | — | EP | claimed |
| US-4304779-A | 6-(Nitrogen-containing heterocyclic)hydroxymethylpenicillanic acids, compounds related thereto and processes for their preparation | SCHERING CORPORATION (US) | 1981-12-08 | — | — | US | claimed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| US-4252807-A | Fused pyrimidine derivatives and antiatherosclerotic methods of treatment with them | CHINCIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1981-02-24 | — | — | US | claimed |
| EP-0005014-A1 | Clavulanic acid derivatives, preparation and compositions | BEECHAM GROUP PLC (GB) | 1979-10-31 | — | — | EP | claimed |
| US-4048171-A | 1,4-Dihydropyridines | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | claimed |
| US-4031226-A | ANTIEMETIC, PSYCHOTROPIC | JANSSEN PHARMACEUTICA N.V. (BE) | 1977-06-21 | — | — | US | claimed |
| US-3998834-A | ANALGESICS | JANSSEN PHARMACEUTICA N.V. (BE) | 1976-12-21 | — | — | US | claimed |
| US-3957993-A | ADMINISTERING | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-05-18 | — | — | US | claimed |