SCHEMBL13801030

SCHEMBL13801030

C=C(C)C(=O)OCCCC(O)c1c2ccccc2cc2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.40
POLB P06746 1/20 0.40
APEX1 P27695 1/20 0.40
HTT P42858 1/20 0.40
TSHR P16473 3/20 0.40
THRB P10828 1/20 0.35
ALDH1A1 P00352 4/20 0.34
HPGD P15428 4/20 0.34
KDM4E B2RXH2 3/20 0.34
GLA P06280 2/20 0.34
MAPT P10636 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
ATM Q13315 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13801028 0.94 TDP1 (0.36) TDP1POLBAPEX1HTTTSHR
SCHEMBL4145012 0.82 HTT (0.43) TDP1POLBAPEX1HTTTSHR
SCHEMBL13801026 0.80 HDAC1 (0.50) TDP1POLBAPEX1HTTTSHR
SCHEMBL28989675 0.79 TSHR (0.45) TDP1POLBAPEX1HTTTSHR
SCHEMBL21385822 0.79 POLB (0.51) TDP1POLBAPEX1HTTTSHR
SCHEMBL13801022 0.78 POLB (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL15751387 0.78 TSHR (0.48) TDP1POLBAPEX1HTTTSHR
SCHEMBL28989837 0.78 TSHR (0.48) TDP1POLBAPEX1HTTTSHR
SCHEMBL10035133 0.78 TSHR (0.48) TDP1POLBAPEX1HTTTSHR
SCHEMBL5594535 0.77 RAD52 (0.45) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods CHEIL INDUSTRIES, INC. (KR) 2009-06-18 US disclosed
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods CHEIL INDUSTRIES, INC. (KR) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods AHR, PAH, MCHR1 TDP1 1662/4885POLB 2093/4885APEX1 787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.