SCHEMBL13801022

SCHEMBL13801022

C=C(C)C(=O)OCCCC(O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.49
TDP1 Q9NUW8 2/20 0.49
APEX1 P27695 1/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
LMNA P02545 2/20 0.47
TSHR P16473 3/20 0.46
HPGD P15428 1/20 0.42
RIPK1 Q13546 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.40
PPARG P37231 1/20 0.39
PPARA Q07869 1/20 0.39
CHRM2 P08172 1/20 0.38
CHRM1 P11229 1/20 0.38
CHRM3 P20309 1/20 0.38
CHRNB2 P17787 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13801021 0.92 HPGD (0.44) POLBTDP1APEX1HTTSMN1; SMN2
SCHEMBL15901492 0.89 TDP1 (0.50) POLBTDP1APEX1HTTSMN1; SMN2
SCHEMBL14192618 0.87 TDP1 (0.48) POLBTDP1APEX1HTTSMN1; SMN2
SCHEMBL27389835 0.84 TSHR (0.46) POLBTDP1APEX1HTTSMN1; SMN2
SCHEMBL235139 0.84 MTNR1A (0.49) POLBTDP1APEX1HTTLMNA
SCHEMBL13801026 0.84 HDAC1 (0.50) POLBTDP1APEX1HTTTSHR
SCHEMBL21837193 0.83 CHRNB2 (0.57) POLBTDP1APEX1HTTLMNA
SCHEMBL1685754 0.83 TSHR (0.50) POLBTDP1APEX1HTTSMN1; SMN2
Hydrochloric Acid SCHEMBL19281734 0.82 CHRNB2 (0.56) POLBTDP1APEX1HTTSMN1; SMN2
SCHEMBL29085549 0.82 TDP1 (0.47) POLBTDP1APEX1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods CHEIL INDUSTRIES, INC. (KR) 2009-06-18 US disclosed
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods CHEIL INDUSTRIES, INC. (KR) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods AHR, PAH, MCHR1 POLB 2093/4885TDP1 1662/4885APEX1 787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.