Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 9/20 | 1.00 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 7/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4235959 | 0.84 | KCNA5 (0.73) | KCNA5KCNA3CNR1CNR2 | |
| SCHEMBL4235964 | 0.84 | KCNA5 (0.73) | KCNA5KCNA3CNR1CNR2 | |
| SCHEMBL13801062 | 0.83 | KCNA5 (0.82) | KCNA5KCNA3 | |
| SCHEMBL6763911 | 0.77 | KCNA5 (0.61) | KCNA5CNR1CNR2 | |
| SCHEMBL6184714 | 0.73 | KCNA5 (0.57) | KCNA5KCNA3GRIN2B | |
| SCHEMBL2212471 | 0.72 | KCNA5 (1.00) | KCNA5KCNA3 | |
| SCHEMBL498107 | 0.72 | KCNA5 (1.00) | KCNA5KCNA3 | |
| SCHEMBL498106 | 0.72 | KCNA5 (1.00) | KCNA5KCNA3 | |
| SCHEMBL12434370 | 0.71 | KCNA5 (0.55) | KCNA5KCNA3 | |
| SCHEMBL12434375 | 0.70 | KCNA5 (0.67) | KCNA5KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090149496-A1 | INHIBITORS OF THE TASK-1 AND TASK-3 ION CHANNEL | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-06-11 | — | — | US | disclosed |
| US-20090149496-A1 | INHIBITORS OF THE TASK-1 AND TASK-3 ION CHANNEL | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149496-A1 | INHIBITORS OF THE TASK-1 AND TASK-3 ION CHANNEL | KCNN3, CACNA1I, KCNN1 | KCNA5 67/4885KCNA3 28/4885GRIN2B 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.