Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.59 |
| ▸ | CCR5 | P51681 | 1/20 | 0.59 |
| ▸ | CCR8 | P51685 | 1/20 | 0.59 |
| ▸ | KDM1A | O60341 | 6/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987521 | 0.82 | CCR1 (0.61) | CCR1CCR5CCR8CYP2A6RAB9A | |
| SCHEMBL15476086 | 0.81 | CCR1 (0.59) | CCR1CCR5CCR8KDM1ACYP2A6 | |
| SCHEMBL12390293 | 0.79 | KDM1A (0.51) | CCR1CCR5CCR8KDM1AHDAC1 | |
| SCHEMBL21913721 | 0.79 | CCR1 (0.57) | CCR1CCR5CCR8KDM1ACYP2A6 | |
| SCHEMBL4509227 | 0.79 | CCR1 (0.57) | CCR1CCR5CCR8CYP2A6RAB9A | |
| SCHEMBL12303171 | 0.79 | CCR1 (0.57) | CCR1CCR5CCR8CYP2A6RAB9A | |
| SCHEMBL5903098 | 0.79 | CCR1 (0.57) | CCR1CCR5CCR8CYP2A6MAOA | |
| SCHEMBL23599062 | 0.79 | KDM1A (0.48) | KDM1AHDAC1HDAC2HDAC6MAOA | |
| SCHEMBL25256386 | 0.79 | KDM1A (0.51) | KDM1AHDAC1HDAC2HDAC6MAOA | |
| SCHEMBL15655681 | 0.78 | CCR1 (0.55) | CCR1CCR5CCR8KDM1ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | GNRHR, PGR, MC1R | CCR1 1717/4885CCR5 3219/4885CCR8 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.