Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTAP | Q13126 | 13/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737297 | 1.00 | MTAP (0.47) | MTAPNPC1RAB9ASMN1; SMN2DRD1 | |
| SCHEMBL4737296 | 0.89 | MTAP (0.58) | MTAP | |
| SCHEMBL13801684 | 0.89 | MTAP (0.58) | MTAP | |
| SCHEMBL4736667 | 0.85 | PNP (0.34) | MTAPDRD1 | |
| SCHEMBL12715593 | 0.85 | PNP (0.34) | MTAPDRD1 | |
| SCHEMBL4751248 | 0.75 | PDCD1 (0.38) | DRD1 | |
| SCHEMBL1573414 | 0.70 | MTAP (0.49) | MTAPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4736602 | 0.67 | CYP2C19 (0.41) | NPC1RAB9ASMN1; SMN2DRD1 | |
| SCHEMBL4736590 | 0.66 | CYP2C19 (0.37) | NPC1RAB9ASMN1; SMN2DRD1 | |
| SCHEMBL24063045 | 0.64 | MTAP (1.00) | MTAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7553839-B2 | 5h-pyrrolo[3,2-D] pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases | INDUSTRIAL RESEARCH LIMITED (NZ) | 2009-06-30 | — | — | US | disclosed |