Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519179 | 0.91 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL1380840 | 0.84 | KCNH2 (0.38) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1385514 | 0.83 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL4505620 | 0.83 | KCNH2 (0.36) | KCNH2SCN5A | |
| SCHEMBL4516781 | 0.83 | KCNH2 (0.36) | KCNH2SCN5A | |
| SCHEMBL1382762 | 0.82 | KCNH2 (0.38) | KCNH2SCN5A | |
| SCHEMBL1382756 | 0.82 | KCNH2 (0.38) | KCNH2SCN5A | |
| SCHEMBL1382759 | 0.82 | KCNH2 (0.38) | KCNH2SCN5A | |
| SCHEMBL7552000 | 0.82 | KCNH2 (0.40) | KCNH2SCN5ACYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL4512744 | 0.81 | KCNH2 (0.37) | KCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4811978-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| EP-1255739-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2002-11-13 | — | — | EP | claimed |
| WO-2001053273-A1 | 3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 2001-07-26 | — | — | WO | claimed |