SCHEMBL1380415

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1381096	0.89	NOS3 (0.38)	NOS3NOS2MCHR1TAAR1CYP3A4
	SCHEMBL1382290	0.85	KCNA5 (0.46)	SLC6A2SLC6A4SLC6A3KCNH2MPO
	SCHEMBL29598348	0.82	—	—
	SCHEMBL331709	0.82	—	—
	SCHEMBL1381048	0.82	CDC7 (0.34)	CYP3A4CYP2D6SLC6A2SLC6A4SLC6A3
	SCHEMBL13716097	0.78	KCNA5 (0.38)	MCHR1CYP3A4CYP2D6SLC6A2SLC6A4
	SCHEMBL2936969	0.76	TAAR1 (0.54)	TAAR1CYP3A4CYP2D6SLC6A2SLC6A4
	SCHEMBL29793607	0.76	TAAR1 (0.54)	TAAR1CYP3A4CYP2D6SLC6A2SLC6A4
	SCHEMBL30824556	0.76	TAAR1 (0.54)	TAAR1CYP3A4CYP2D6SLC6A2SLC6A4
	SCHEMBL18793289	0.76	TAAR1 (0.54)	TAAR1CYP3A4CYP2D6SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.