Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 4/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9105151 | 0.92 | RAF1 (0.50) | RAF1MAPTMEN1KMT2ALMNA | |
| SCHEMBL4466716 | 0.86 | RAF1 (0.65) | RAF1MEN1KMT2ARETKDR | |
| SCHEMBL9101755 | 0.82 | RET (0.55) | RAF1MEN1KMT2ARETKDR | |
| SCHEMBL9098846 | 0.78 | KDR (0.49) | RAF1MAPTRETKDRCDK8 | |
| SCHEMBL4466558 | 0.76 | RET (0.71) | RAF1MEN1KMT2ARETKDR | |
| SCHEMBL9099762 | 0.76 | KDR (0.42) | RAF1MAPTRETRAB9AKDR | |
| SCHEMBL5724635 | 0.75 | KDR (0.53) | RAF1RETRAB9AKDRCDK8 | |
| SCHEMBL9100193 | 0.75 | CDK8 (0.42) | RAF1MEN1KMT2ALMNARET | |
| SCHEMBL9102135 | 0.74 | RAF1 (0.55) | RAF1MEN1KMT2ARETKDR | |
| SCHEMBL9102040 | 0.74 | CDK8 (0.45) | MAPTMEN1KMT2ALMNARET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4805839-B2 | — | — | 2011-11-02 | — | — | JP | claimed |