Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8438204 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2TDP1ATM | |
| SCHEMBL14874211 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1SMN1; SMN2TDP1ATM | |
| Hydrochloric Acid SCHEMBL28558936 | 0.98 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2TDP1ATM | |
| SCHEMBL26207326 | 0.90 | MAPT (0.54) | KDM4EALDH1A1SMN1; SMN2TDP1ATM | |
| SCHEMBL20502983 | 0.89 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2TDP1ATM | |
| SCHEMBL4513801 | 0.87 | ALDH1A1 (0.63) | KDM4EALDH1A1SMN1; SMN2TDP1ATM | |
| SCHEMBL4517151 | 0.87 | ALDH1A1 (0.63) | KDM4EALDH1A1SMN1; SMN2TDP1ATM | |
| SCHEMBL8872114 | 0.86 | KDM4E (0.66) | KDM4EALDH1A1SMN1; SMN2TDP1ATM | |
| SCHEMBL4514426 | 0.86 | ALDH1A1 (0.62) | KDM4EALDH1A1SMN1; SMN2TDP1ATM | |
| SCHEMBL7925245 | 0.86 | ALDH1A1 (0.62) | KDM4EALDH1A1SMN1; SMN2TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070485-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |