Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | YAP1 | P46937 | 1/20 | 0.55 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13805206 | 0.91 | GAA (0.59) | CNR1PKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13804995 | 0.87 | LSS (0.56) | ALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL13805196 | 0.87 | CNR1 (0.67) | CNR1PKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13805178 | 0.86 | PKM (0.54) | CNR1PKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13805065 | 0.84 | KMT2A (0.60) | ALDH1A1SMN1; SMN2POLBKMT2ALMNA | |
| SCHEMBL13805202 | 0.84 | CNR1 (0.51) | CNR1PKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5748257 | 0.84 | PTGDR (0.56) | GAAKMT2ALMNA | |
| SCHEMBL13805135 | 0.83 | MEN1 (0.53) | ALDH1A1SMN1; SMN2POLBKMT2ALMNA | |
| SCHEMBL13815164 | 0.83 | PTGDR2 (0.46) | CNR1PKMGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL13805236 | 0.83 | PTGDR2 (0.46) | CNR1PKMGAAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090143396-A1 | Sulfonyl-Substituted Aryl Compounds as Modulators of Peroxisome Proliferator Activated Receptors | MALECHA JAMES W | 2009-06-04 | — | — | US | disclosed |
| US-20090143396-A1 | Sulfonyl-Substituted Aryl Compounds as Modulators of Peroxisome Proliferator Activated Receptors | MALECHA JAMES W | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143396-A1 | Sulfonyl-Substituted Aryl Compounds as Modulators of Peroxisome Proliferator Activated Receptors | PPARG, PPARA, PPARD | CNR1 88/4885PKM 828/4885GAA 341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.