SCHEMBL13805791

SCHEMBL13805791

CN(C)C1=NN(C)C(=O)/C1=C/C=C1/Oc2ccccc2N1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.37
▸ MEN1 O00255 5/20 0.37
▸ KMT2A Q03164 5/20 0.37
▸ ALDH1A1 P00352 5/20 0.37
▸ MAPK1 P28482 4/20 0.37
▸ HTT P42858 4/20 0.37
▸ TDP1 Q9NUW8 2/20 0.34
▸ TNNI3 P19429 1/20 0.34
▸ TNNT2 P45379 1/20 0.34
▸ TNNC1 P63316 1/20 0.34
▸ SMN1; SMN2 Q16637 3/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ USP2 O75604 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ APP P05067 2/20 0.33
▸ SNCA P37840 2/20 0.33
▸ P2RX4 Q99571 1/20 0.33
▸ GAA P10253 4/20 0.32
▸ KDM4E B2RXH2 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14016488 0.83 MEN1 (0.36) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL13683528 0.82 MEN1 (0.36) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL13683534 0.82 P2RX4 (0.38) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL13683511 0.81 ALDH1A1 (0.39) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL13683529 0.81 MEN1 (0.36) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL13683513 0.81 MEN1 (0.36) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL13683512 0.81 MEN1 (0.35) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL13683533 0.80 ALDH1A1 (0.36) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL13683527 0.80 ALDH1A1 (0.34) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL13683539 0.77 KDM4E (0.36) MAPTMEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7553797-B2 Thermal transfer recording material and thermal transfer recording method KONICA MINOLTA PHOTO IMAGING, INC. (JP) 2009-06-30 — — US disclosed
US-7553797-B2 Thermal transfer recording material and thermal transfer recording method KONICA MINOLTA PHOTO IMAGING, INC. (JP) 2009-06-30 — — US disclosed
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