Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.47 |
| ▸ | DRD3 | P35462 | 7/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | SORD | Q00796 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509153 | 0.90 | DRD2 (0.51) | DRD2DRD3HTR1AHTR2ADRD4 | |
| SCHEMBL12509046 | 0.85 | DRD2 (0.55) | DRD2DRD3HTR1AHTR2AHCAR2 | |
| SCHEMBL12509223 | 0.81 | HCAR2 (0.50) | DRD2DRD3HTR1AHTR2AHCAR2 | |
| SCHEMBL12509345 | 0.80 | HCAR2 (0.52) | DRD2DRD3HTR1AHTR2ADRD4 | |
| SCHEMBL12509220 | 0.79 | TRPV1 (0.52) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL1532949 | 0.75 | DRD2 (0.50) | DRD2DRD3HTR1AHTR2AHRH4 | |
| SCHEMBL12736157 | 0.75 | HTR2C (0.61) | DRD2DRD3HTR1AHRH4DRD4 | |
| Hydrochloric Acid SCHEMBL1532724 | 0.74 | HTR2C (0.60) | DRD2DRD3HTR1AHRH4DRD4 | |
| SCHEMBL19753624 | 0.71 | DRD2 (0.68) | DRD2DRD3HTR1AHTR2ADRD4 | |
| SCHEMBL9224900 | 0.71 | HRH4 (0.63) | DRD2DRD3HTR1AHRH4DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |