Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.41 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL603497 | 0.90 | HRH4 (0.43) | HTR7TERTNPY5RHRH4 | |
| SCHEMBL604898 | 0.83 | KCNH2 (0.43) | HTR7TERTNPY5RHRH4P2RX7 | |
| SCHEMBL605431 | 0.76 | HRH4 (0.55) | TERTHRH4 | |
| SCHEMBL603959 | 0.75 | HRH4 (0.54) | HTR7TERTHRH4DRD3 | |
| SCHEMBL4006179 | 0.71 | PIN1 (0.40) | — | |
| SCHEMBL605879 | 0.69 | HRH4 (0.45) | TERTHRH4P2RX7 | |
| SCHEMBL604889 | 0.67 | HRH4 (0.46) | HRH4 | |
| SCHEMBL602990 | 0.65 | HRH4 (0.45) | TERTHRH4DRD3 | |
| SCHEMBL603755 | 0.65 | HRH4 (0.43) | TERTHRH4DRD3 | |
| SCHEMBL1625491 | 0.65 | HRH4 (0.62) | HRH4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009079001-A1 | BICYCLIC HETEROARYL-SUBSTITUTED IMIDAZOLES AS MODULATORS OF THE HISTAMINE H4 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-06-25 | — | — | WO | disclosed |