SCHEMBL13808488

SCHEMBL13808488

Cc1cccc(C[C@](O)(CC(C)(C)c2ccccc2)C(=O)Nc2ccc3c(=O)onc(C)c3c2)c1

nearest known ligand 0.88

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 19/20 0.88
PGR P06401 17/20 0.88
NR3C2 P08235 7/20 0.67
AR P10275 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3995793 1.00 NR3C1 (0.88) NR3C1PGRNR3C2AR
SCHEMBL4002888 0.94 NR3C1 (1.00) NR3C1PGRNR3C2AR
SCHEMBL3998324 0.92 NR3C1 (0.87) NR3C1PGRNR3C2AR
SCHEMBL3997394 0.91 NR3C1 (0.91) NR3C1PGRNR3C2AR
SCHEMBL3997219 0.90 NR3C1 (0.83) NR3C1PGRNR3C2AR
SCHEMBL3995881 0.89 NR3C1 (0.90) NR3C1PGRNR3C2AR
SCHEMBL13909210 0.88 NR3C1 (0.67) NR3C1PGRNR3C2AR
SCHEMBL4176693 0.88 NR3C1 (0.67) NR3C1PGRNR3C2AR
SCHEMBL3993440 0.87 NR3C1 (0.87) NR3C1PGRNR3C2AR
SCHEMBL3994899 0.87 NR3C1 (0.85) NR3C1PGRNR3C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009071252-A1 NONSTEROIDAL PROGESTERONE RECEPTOR MODULATORS BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-06-11 WO disclosed