Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.58 |
| ▸ | RORC | P51449 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 3/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30693221 | 1.00 | SLC6A4 (0.58) | SLC6A4RORCSLC6A3SLC6A2F10 | |
| SCHEMBL1970755 | 1.00 | SLC6A4 (0.58) | SLC6A4RORCSLC6A3SLC6A2F10 | |
| SCHEMBL16070079 | 1.00 | SLC6A4 (0.58) | SLC6A4RORCSLC6A3SLC6A2F10 | |
| SCHEMBL7888069 | 0.91 | RORC (0.57) | SLC6A4RORCSLC6A3SLC6A2F10 | |
| SCHEMBL14498495 | 0.91 | RORC (0.57) | SLC6A4RORCSLC6A3SLC6A2F10 | |
| SCHEMBL4661703 | 0.91 | RORC (0.57) | SLC6A4RORCSLC6A3SLC6A2F10 | |
| SCHEMBL4661705 | 0.91 | RORC (0.57) | SLC6A4RORCSLC6A3SLC6A2F10 | |
| SCHEMBL5110560 | 0.91 | RORC (0.57) | SLC6A4RORCSLC6A3SLC6A2F10 | |
| SCHEMBL23951589 | 0.89 | RORC (0.56) | SLC6A4RORCSLC6A3SLC6A2 | |
| SCHEMBL2224784 | 0.89 | RORC (0.56) | SLC6A4RORCSLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530222-A | Pyrrolidine compound and application thereof | 上海交通大学医学院附属瑞金医院 | 2024-08-23 | — | — | CN | disclosed |
| EP-1957450-B1 | SEROTONIN TRANSPORTER (SERT) INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-06-24 | — | — | EP | disclosed |
| WO-2007063009-A1 | SEROTONIN TRANSPORTER (SERT) INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-07 | — | — | WO | disclosed |