Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Isoleucine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 12/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.38 |
| ▸ | FAP | Q12884 | 2/20 | 0.38 |
| ▸ | PRCP | P42785 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoleucine SCHEMBL5017800 | 1.00 | DPP4 (0.40) | DPP4NOS2NOS3NOS1DPP8 | |
| Isoleucine SCHEMBL28231733 | 1.00 | DPP4 (0.40) | DPP4NOS2NOS3NOS1DPP8 | |
| Isoleucine SCHEMBL703839 | 1.00 | DPP4 (0.40) | DPP4NOS2NOS3NOS1DPP8 | |
| Isoleucine SCHEMBL138092 | 1.00 | DPP4 (0.40) | DPP4NOS2NOS3NOS1DPP8 | |
| Isoleucine SCHEMBL1537461 | 1.00 | DPP4 (0.40) | DPP4NOS2NOS3NOS1DPP8 | |
| Isoleucine SCHEMBL1537458 | 1.00 | DPP4 (0.40) | DPP4NOS2NOS3NOS1DPP8 | |
| Isoleucine SCHEMBL1537322 | 1.00 | DPP4 (0.40) | DPP4NOS2NOS3NOS1DPP8 | |
| Isoleucine SCHEMBL1537321 | 1.00 | DPP4 (0.40) | DPP4NOS2NOS3NOS1DPP8 | |
| Isoleucine SCHEMBL6535295 | 0.97 | DPP4 (0.39) | DPP4NOS2NOS3NOS1DPP8 | |
| Isoleucine SCHEMBL3692760 | 0.97 | DPP4 (0.39) | DPP4NOS2NOS3NOS1DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026100273-A1 | METHOD FOR PRODUCING USEFUL SUBSTANCE, CULTURE SOLUTION FOR CULTURING ALGAE, APPARATUS FOR PRODUCING USEFUL SUBSTANCE, AND ALGAE CONTAINING USEFUL SUBSTANCE | ＮＴＴ株式会社 | 2026-05-15 | — | — | WO | claimed |
| US-11272717-B2 | Edible water-in-oil emulsion and a process for preparing such emulsion | Upfield Europe B.V. (NL) | 2022-03-15 | — | — | US | claimed |
| EP-3134105-B1 | PEPTIDE ANALOGUES WITH BRANCHED AMINO ACID PROBE(S) | TXP PHARMA GMBH (CH) | 2020-11-18 | — | — | EP | claimed |
| EP-2900206-B1 | USE OF A COMBINATION OF AT LEAST ONE POLYUNSATURATED FATTY ACID AND AT LEAST ONE CAROTENOID, FOR IMPROVING THE QUALITY OF THE NAILS | NUTRICOS TECH (FR) | 2019-07-31 | — | — | EP | claimed |
| US-9642786-B2 | Use of a combination of at least one polyunsaturated fatty acid and at least one carotenoid, for improving the quality of the nails | NUTRICOS TECHNOLOGIES (FR) | 2017-05-09 | — | — | US | claimed |
| US-20150250691-A1 | USE OF A COMBINATION OF AT LEAST ONE POLYUNSATURATED FATTY ACID AND AT LEAST ONE CAROTENOID, FOR IMPROVING THE QUALITY OF THE NAILS | NUTRICOS TECHNOLOGIES (FR) | 2015-09-10 | — | — | US | claimed |
| US-20150208683-A1 | EDIBLE WATER-IN-OIL EMULSION AND A PROCESS FOR PREPARING SUCH EMULSION | CONOPCO, INC., D/B/A UNILEVER (US) | 2015-07-30 | — | — | US | claimed |
| EP-2482678-B1 | CHEESE AND METHOD FOR ITS MANUFACTURING | VALIO LTD (FI) | 2013-07-10 | — | — | EP | claimed |
| EP-2482678-A1 | CHEESE AND METHOD FOR ITS MANUFACTURING | Valio Ltd. (FI) | 2012-08-08 | — | — | EP | claimed |
| US-20120183644-A1 | CHEESE AND METHOD FOR ITS MANUFACTURING | VALIO LTD. (FI) | 2012-07-19 | — | — | US | claimed |
| EP-2398335-A1 | PROCESS FOR IMPROVING TASTE OF FOOD PRODUCT | Valio Ltd. (FI) | 2011-12-28 | — | — | EP | claimed |
| WO-2011039414-A1 | CHEESE AND METHOD FOR ITS MANUFACTURING | VALIO LTD (FI) | 2011-04-07 | — | — | WO | claimed |
| WO-2010094839-A1 | PROCESS FOR IMPROVING TASTE OF FOOD PRODUCT | VALIO LTD (FI) | 2010-08-26 | — | — | WO | claimed |
| WO-2010023364-A1 | PROCESS FOR IMPROVING TASTE OF PRODUCT | VALIO LTD (FI) | 2010-03-04 | — | — | WO | claimed |
| WO-2026100273-A1 | METHOD FOR PRODUCING USEFUL SUBSTANCE, CULTURE SOLUTION FOR CULTURING ALGAE, APPARATUS FOR PRODUCING USEFUL SUBSTANCE, AND ALGAE CONTAINING USEFUL SUBSTANCE | ＮＴＴ株式会社 | 2026-05-15 | — | — | WO | disclosed |
| EP-3995139-B1 | COMPOSITION FOR USE IN TREATING CANCER | UNIV GEORGIA STATE RES FOUND (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-4097145-B1 | REDUCTION OF ADSORPTION | LEUKOCARE AG (DE) | 2026-01-28 | — | — | EP | disclosed |
| US-20090298773-A1 | METHODS OF PRODUCING FUNCTIONAL MISO | MARUKOME CO., LTD. (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-1485119-A1 | ENHANCING THE AVAILABILITY OF MINERALS BY USING BIOLOGICALLY ACTIVE PEPTIDES | Valio Ltd. (FI) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003070267-A1 | ENHANCING THE AVAILABILITY OF MINERALS BY USING BIOLOGICALLY ACTIVE PEPTIDES | VALIO LTD (FI) | 2003-08-28 | — | — | WO | disclosed |