Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23330238 | 0.97 | ALDH1A1 (0.57) | ALDH1A1TTRTSHR | |
| SCHEMBL10503991 | 0.94 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL7998866 | 0.94 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL9377210 | 0.94 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL9833688 | 0.94 | ALDH1A1 (0.47) | ALDH1A1 | |
| Biphenyl SCHEMBL5182785 | 0.90 | ALDH1A1 (0.57) | ALDH1A1TTRTSHRSLC18A3MAPT | |
| SCHEMBL16877673 | 0.90 | ALDH1A1 (0.47) | ALDH1A1TTRTSHR | |
| Dioxane SCHEMBL28220207 | 0.86 | ALDH1A1 (0.61) | ALDH1A1TTRTSHRMAPTNPSR1 | |
| SCHEMBL23682710 | 0.86 | TTR (0.42) | ALDH1A1TTRTSHR | |
| SCHEMBL21841419 | 0.85 | ALDH1A1 (0.44) | ALDH1A1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567453-A | Benzazepine analogs as inhibitors of bruton's tyrosine kinase | 渤健马萨诸塞州股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-110621670-B | Benzazepine analogs as inhibitors of bruton's tyrosine kinase | 比奥根MA公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-114555588-A | Quinazolines as AXL inhibitors | 南京正大天晴制药有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-20210228723-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | Design Therapeutics, Inc. | 2021-07-29 | — | — | US | disclosed |
| EP-1333319-B1 | Silver halide photographic light-sensitive material | FUJIFILM CORP (JP) | 2009-06-10 | — | — | EP | disclosed |
| EP-1521116-B1 | Silver halide photographic light-sensitive material and package thereof | FUJIFILM CORP (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-1465008-B1 | Silver halide photographic light-sensitive material | FUJIFILM CORP (JP) | 2008-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210228723-A1 | METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE | ZFX, F13B, GRN | ALDH1A1 4687/4885TTR 516/4885TSHR 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.